As the metal complex compound sterile and has anti-inflammatory and antimicrobial action. Accelerates reparative processes in the skin and reduces inflammation (erythema, edema, infiltration), promotes the disappearance of itching. The presence of bound molecules and glycerol titanium atom in the molecule provides a protective dehydrating, decongestant. local analgesic effect.
The molecule anastrozole side effects titanium atom chemically bound to glycerol, is a hub for constituting a complexing molecule fragments of the drug: glycerol and water. This interaction is determined bystructure providing its conductivity through biological tissue and its pharmacological properties. Promotes drugs through the skin and mucous membranes.
When topically rapidly absorbed, distributed in the skin, subcutaneous tissue and underlying tissues. Do not metabolized. Provided intact kidneys 42% 48% through the intestines, 6.2% sweat glands, mucosal airway 3.8%. The rate of elimination of the drug 20-24 h. Does not accumulate in the body.
Indications for use :
– Bursitis, arthritis, tendonitis, tenosynovitis,
– psoriasis, atopic dermatitis, seborrheic eczema, dermatitis, scleroderma, lichen planus,
– as a topical radioprotective radiation therapy;
– conductor as medicaments.
: Hypersensitivity to anastrozole side effects, acute inflammatory diseases of the skin and mucous membranes, purulent wounds with pronounced symptoms of exudation.
Pregnancy and lactation
Insufficient data but use of the drug during pregnancy and lactation.
Dosage and administration
for local and external.
Apply to the affected skin and mucous thin layer 1-3 times a day. The course of treatment is individual, depends on the severity of the disease, the location and the severity of the process. The effect of the drug occurs within the first week of treatment. Possible repeated courses of treatment and long-term use within 2-3 months.
In applying the drug as a topical radioprotective agent for protection against radiation injuries applied thinly to the area of irradiation before a session and 12 hours thereafter. After the application is necessary to avoid contact with clothing, do not use occlusive dressings. In the presence of local radiation drug reactions used to its disappearance.
Rarely in the first few minutes after application to the skin or mucous possibly tingling, tingling, feeling of tightness, passing on their own and do not require discontinuation of therapy. When individual sensitivity may be local allergic reactions. In this case, the use anastrozole side effects stopped.
Interactions with other drugs
have been reported.
As the gel complexing system, combined with a number of drug substances with different chemical composition and structure, and can be used as a basis for the preparation of soft medicinal forms.